NURS 3100 Exam 1 Practice

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Which substance has the lowest rate of crossing renal tubular membranes and would be excreted in urine?

Ionized drugs
Lipid-soluble drugs
Non-ionized drugs
Volatile drugs

The correct answer is: Ionized drugs

Ionized drugs have the lowest rate of crossing renal tubular membranes and would be excreted in urine. This is because ionized drugs have a charge which makes it more difficult for them to pass through the lipid-rich membranes of the renal tubules. On the other hand, lipid-soluble drugs, non-ionized drugs, and volatile drugs can more easily cross membranes and are more likely to be reabsorbed rather than excreted in urine.