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Which of the following describes a Category D medication concerning pregnancy?

  1. Evidence of human fetal risk exists, and the risk outweighs the benefits

  2. No confirmed risk for fetal abnormalities

  3. High risk of causing fetal abnormalities

  4. Benefits may warrant use of the drug in pregnant women despite potential risks

The correct answer is: Evidence of human fetal risk exists, and the risk outweighs the benefits

Category D medications are those where there is evidence of human fetal risk, and the potential benefits of the medication may outweigh the risks in certain situations. It is important for healthcare providers to carefully weigh the risks and benefits when considering the use of Category D medications during pregnancy. Option A correctly describes a Category D medication by highlighting that there is evidence of fetal risk, and this risk is considered to outweigh the potential benefits of using the medication during pregnancy. Option B is incorrect because Category D medications are not considered to have no confirmed risk for fetal abnormalities. Option C is incorrect as Category D medications are not synonymous with having a high risk of causing fetal abnormalities. Option D is incorrect because Category D medications are ones where the benefits may warrant use of the drug in pregnant women despite potential risks, which is the opposite of what is stated in this option.