NURS 3100 Exam 1 Practice

What is the primary objective of the preclinical investigation phase in drug development?

1. Assessing drug safety and biological activity in laboratory animals

2. Testing the drug on a small group of healthy volunteers

3. Evaluating the drug's effect on patients with the target disease

4. Conducting long-term studies on drug efficacy and adverse effects

The correct answer is: Assessing drug safety and biological activity in laboratory animals

The primary objective of the preclinical investigation phase in drug development is to assess drug safety and biological activity in laboratory animals. This phase involves testing the drug in vitro and in vivo to determine its safety profile, potential toxicity, pharmacokinetics, and pharmacodynamics before human trials can begin. It is essential to thoroughly evaluate these aspects in preclinical studies to ensure that the investigational drug has an acceptable safety profile and shows promise in treating the target disease. Options B, C, and D are not the primary objectives of the preclinical investigation phase in drug development.