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The nurse is preparing to administer a medication to a client on a medical-surgical unit. The median lethal dose of the drug is 40 mg, and the median effective dose of the drug is 10 mg. What is the therapeutic index?

  1. 4

  2. 3

  3. 2

  4. 5

The correct answer is: 4

The therapeutic index is calculated by dividing the median lethal dose (40 mg) by the median effective dose (10 mg). In this case, 40 mg/10 mg = 4. Therefore, the therapeutic index for this medication is 4, making option A the correct answer. Options B, C, and D are incorrect as they do not accurately reflect the calculated therapeutic index in this scenario.