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A nurse employed by the FDA is involved in clinical investigation. The nurse's primary role in this phase of FDA review and approval is to perform tests on which of the following?

  1. Human clients

  2. Human cell cultures in the lab

  3. The population at large

  4. Various species of animals

The correct answer is: Human clients

In clinical investigation, nurses employed by the FDA primarily perform tests on human clients. This is because the focus of clinical investigation is on studying the effects of drugs, treatments, or medical devices on human individuals. While human cell cultures in the lab, the population at large, and various species of animals can also be used in research studies, the primary emphasis in clinical investigation is on human subjects to gather data and evaluate the effectiveness and safety of interventions before they are approved for public use.